Cyclospora Multi-Cluster Epidemiological Investigator

Surveillance Lag Deconvolution & Multi-Echelon Supply Chain Traceback
Total Surveillance Cases
1,420
Across 18 Reporting States
Isolated Contamination Vectors
4 Clusters
Odds Ratios 4.8 to 11.2 (p<0.001)
Median Diagnostic Lag
19 Days
Deconvolution window 14-35d
Sporadic / Background Ratio
28.0%
398 Unlinked Seasonal Cases
Epidemic Curve: True Onset vs Reported Lag
19d
Epidemiological Reality: When adjusting for the 19-day testing delay, raw notification spikes collapse into 4 distinct asynchronous agricultural harvest waves rather than a single uncontrolled outbreak.
Multi-Echelon Produce Traceback Network
Traceback Convergence: Identified 4 mutually exclusive distribution bottlenecks (Farms A, B, C, D) clearing 14 other distributors.
Surveillance Line-List & Genomic Cluster Attribution Matrix
Showing representative confirmed cohorts:
Cluster ID Suspect Commodity Vector Confirmed Cohort Median Onset Reporting Delay Odds Ratio (95% CI) Traceback Chokepoint Genomic WGS Allele Distance
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