Denisova Cave Stratigraphy & Archaic Admixture Simulator Siberia • MIS 9–1

1. Stratigraphic Excavator
EXCAVATION DEPTH: 4.20 m CHRONO-HORIZON: 51.6 - 76.2 kya
Selected Stratum
Layer 11 (East Chamber)
Sediment Microfacies
Loam with limestone debris
Climate (MIS)
MIS 3 / MIS 4 (Interstadial)
Hominin Horizon
Denisovan + Neanderthal
Stratified Fossils & Artifacts
2. Fossil Lab & Genomic Admixture
denisova_3_finger

Denisova 3 (Juvenile Distal Pinky Phalanx)

Excavated from East Chamber Layer 11. Yielded the first high-coverage (30x) Denisovan nuclear genome in 2010 by Svante Pääbo and colleagues.

mtDNA Divergence: 1.04 Mya Coverage: 30.4x Nuclear Sex: Female (XX)
Archaic Introgression Pathways

EPAS1 (Hypoxia pathway adaptive introgression in Tibetan populations)

A 5-SNP Denisovan-derived haplotype on Chromosome 2 prevents excessive hemoglobin production and high-altitude hypoxia polycythemia in Tibetans and Sherpas.

Global Population Archaic Fractions
Oceanian / Papuan 2.4% Nea4.8% Den
East Asian (Han / Tibetan) 2.1% Nea0.2% Den
European (CEU) 1.9% Nea0.0% Den
Field Dossier Diagnostic Log
// Scientific provenance logs ready...
Layer 11 (East Chamber) • Target: EPAS1
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