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Dopamine & Memory Plasticity Simulator

Quantitative STDP & Dendritic Spine Consolidation Lab
Molecular Engine Active
DA: 1.50 μM
Δt: +5.0 ms
Experimental Presets:
🔬 Dendritic Spine & Synaptic Cleft Microstate
AMPA/NMDA
Dopamine (D1)
Active CaMKII
PKA Kinase
📈 Kinase Activation & Weight Change
⏳ 24-Hour Memory Recall Retention
⚙️ Plasticity Parameters
Dopamine Concentration ([DA]) 1.50 μM
Pulse Timing Interval (Δt = t_post - t_pre) +5.0 ms
Baseline Conductance (g_0) 1.00
24h Recall Horizon Inspector 12.0 Hours
📊 Simulated Physiological State
Synaptic Weight (W/W₀) 1.80x
Spine Head Vol (μm³) 0.28 μm³
CaMKII Activity 76.4%
PKA Kinase Level 62.1%
Consolidation T_½ 18.4 hrs
24h Recall Prob 84.2%
📄 Standardized Neuro-Plasticity Snapshot
Model Identity
dopamine-memory-plasticity-sim-57
Dopamine Level ([DA])
1.50 μM
STDP Interval (Δt)
+5.0 ms
Relative Potentiation (ΔW)
+80.0%
Dendritic Spine Volume
0.28 μm³
Predicted 24h Recall Probability
84.2%
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