Apparent Risk Ratio
5.63x
Artificially inflated gap
Low-Eng. Observed Prev.
0.38%
True: 2.80% (38 / 280 diagnosed)
General Observed Prev.
2.14%
True: 2.80% (214 / 280 diagnosed)
2D Population Cohort Matrices (5,000 individuals per subpopulation)
Outer Halo = Diagnosed Clinical Case | Inner Dot = True Condition
Low-Engagement Cohort (e.g. Amish)
38 / 280 Diagnosed
General Population Cohort
214 / 280 Diagnosed
Neurotypical / Unaffected
True Condition (Undiagnosed)
True Condition (Formally Diagnosed)
Epidemiological Proof & Sensitivity Analysis
Ascertainment Bias Factor: 5.63x Distortion
In passive surveillance, the apparent 5.63x difference in observed neurodiversity rates is an artifact of healthcare seeking behavior (15% vs 85%), not underlying biology.
True Underlying Prevalence: 2.80% in both subpopulations (280 cases per 10,000).
Ascertainment Gap Active
[SYSTEM INITIALIZED] Epidemiological Model Loaded.
[BENCHMARK] Standard Passive Clinical Reporting parameters set.