Fertility Clinical Forensic Laboratory
CAP/CLIA AUDIT PROTOCOL 77.2 CASE RECORD LOCK

IVF Clinic Chain of Custody & Match Audit Workbench

Forensic analysis workbench to audit gamete lineage, detect STR allele discrepancies, and evaluate chain of custody risk.

Case Identifier IVF-2026-9041
Clinical Institution Metro Fertility & Reproductive Center
Intended Parents Smith-Davis
Embryo ID / Straw EMB-4492-X
Intended Donor Record DONOR-RES-882
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Audit Status
FLAGGED_CRITICAL_DISCREPANCY
Pedigree exclusion confirmed
Total STR Markers
5
Standard CODIS loci audited
Concordant Matches
4
Alleles match intended parents
Mismatch Count
1
Genetic exclusion points
Chain of Custody Score
75%
3 of 4 stages verified
Legal Exposure Level
Institutional malpractice risk
STR DNA Marker Concordance Analysis
Short Tandem Repeat (STR) profiling of legal mother (Patient A), intended father/donor (Patient B), and transferred embryo/child.
Locus Marker Patient A (Egg) Patient B (Sperm/Donor) Embryo / Child Concordance Status Action
Parentage Rule Definition: An offspring must receive one allele at each locus from biological parent A and one from biological parent B. A locus is deemed a MISMATCH if the child's genotype cannot be mathematically accounted for by the combination of parental alleles.
Chain-of-Custody & Cryo-Log
Track dual-witness verification, canister tank IDs, and liquid nitrogen storage events.
Institutional Risk & Mandatory Actions
Quarantine Storage Tank #4 Cannisters Halt all embryo transfers originating from batch straw batch #4492.
Dual-Technologist Sign-off Audit Investigate missing second witness signature during 2024-03-21 cryopreservation transfer.
Independent CLIA Reference Lab Resequencing Confirm D8S1179 exclusion via 24-STR multiplex capillary electrophoresis.
Formal Patient & Legal Notification Mandatory disclosure under state reproductive medicine licensing guidelines.
Export Forensic Audit Dossier
Generates validated clinical report containing STR profiles, chain-of-custody log, and legal risk classification.
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