🔬 Nanophotonic Malaria Biosensor LSPR Simulator

Biosensor Controls

Clinical Presets

Malaria Target Biomarker

Nanostructure Geometry

Laser Wavelength (λ): 680 nm

Parasitemia Density: 45 p/µL

Microfluidic Flow: 5 µL/min

Nanophotonics Physics: Binding of malaria biomarkers to functionalized gold nanostructures alters the local dielectric refractive index (Δn), inducing a localized surface plasmon resonance shift (Δλ) detected by low-cost photodiode optics.

Flow Chamber & Plasmonic Hotspots Active Flow

LSPR Extinction Spectrum Δλ: +4.2 nm

Resonance Peak

684.2 nm

Spectral Shift (Δλ)

+4.2 nm

Refractive Index (Δn)

+0.018 RIU

Signal-to-Noise (SNR)

14.6 dB

Optical Power Trans.

64.2%

Diagnostic Limit-of-Detection (LOD) Benchmark

Nanophotonic LSPR

LOD: ~1 parasite/µL

DETECTED

Giemsa Smear Microscopy

LOD: 100-200 p/µL

NEGATIVE (Missed)

Rapid Diagnostic Test (RDT)

LOD: 200-500 p/µL

NEGATIVE (Missed)

Clinical Diagnosis: Early / Sub-Microscopic Infection (PFHRP2 Positive). Nanophotonics detects malaria undetectable by conventional field tests.