Real-Time Optical Path & Biocrystal Chamber
532 nm (Green)
Photodiode Voltage
412.5 mV
Extinction Ratio
14.8 dB
Signal-to-Noise (SNR)
26.4 dB
Est. Hemozoin Titer
45 /µL
POSITIVE: Asymptomatic Sub-microscopic Titer
LoD Validated (SNR > 12 dB)
Physics Principle: Plasmodium digests blood hemoglobin into paramagnetic hemozoin biocrystals. Under external magnetic flux (B), hemozoin crystals align, causing optical dichroism and rotating polarized laser light. Functionalized gold nanoparticles (AuNP) trigger localized surface plasmon resonance (LSPR) to boost photon scattering 10× for sub-microscopic titres.
Bench Configurations & Presets
532nm DPSS Green (Optimum Hemozoin Resonance)
45 /µL
0 (Negative)
50 (WHO Micro-threshold)
50,000 (Severe)
0.45 Tesla (Neodymium)
0.0T = Random thermal Brownian motion | 0.8T+ = Full crystalline dipole alignment
90° (Crossed Extinction)
Gold Nanoparticle (AuNP) LSPR Enhancement
Localized Surface Plasmon Resonance amplifies near-field scattering 8.5×
24 dB