Toxidrome Triad
Opioid overdose is characterized by three core clinical indicators:
- Respiratory Depression: Fewer than 8-10 breaths per minute, shallow breathing, gurgling ("death rattle"), or agonal gasping.
- Pinpoint Pupils: Miosis (pupils constricted to small points even in low light).
- Unconsciousness: Deep unresponsiveness to verbal stimuli and vigorous sternal stimulation.