Electrodermal Reactivity (SCR Extinction Trajectory)
● Rested
● Sleep Deprived
Neurobiological Mechanism: vmPFC-Amygdala Circuit Coupling
Top-Down vmPFC Inhibition:
0.32
Ventromedial PFC down-regulation capacity
Amygdala Hyperreactivity:
1.84
Autonomous threat appraisal gain
Clinical Mechanism: Impaired context-safety calibration prevents extinction recall, maintaining threat reactivity even in unreinforced safety spaces.