Vaccine Formulation
Conserved Protein Antigens (Universal Targets)
Polysaccharide Conjugate Platforms (Capsule Specific)
Adjuvant & Immune Stimulator
🛡️
Universal Broad Protection
Conserved surface proteins neutralize both capsule-covered and non-PCV replacement strains.
Bacterial Cell Wall Architecture & Antibody Docking
Opsonophagocytic Activity: Active
Overall Clearance Efficiency
94.8%
5 / 5 Target Strains Controlled
Cross-Serotype Coverage
100%
Pneumococcal Serotype Span
Capsular Escape Risk
Low
Universal Protein Targeted
Bacterial Load (CFU)
52,000
Down from 1,000,000 CFU initial
Invasive Pneumococcal Challenge Panel (5 Challenging Strains)
| Strain / Serotype |
Clinical Relevance |
Capsule Status |
Clearance % |
Outcome |