Clinical Model Parameters
Clinical Presets
7,000+
The Economist reported over 7,000 British patients actively awaiting donor kidneys.
3,100
Combined living and deceased donor kidney transplants per annum in the UK.
12 mo
Expected functioning lifespan of genetically engineered pig-kidney graft.
45%
Proportion of eligible waitlisted cohort opting for bridge xenografting.
Clinical Synthesis & Bridge Impact
Under the baseline British parameters (7,000 on waitlist, 3,100 human donor grafts annually), deploying genetically edited pig-kidneys as a 12-month bridge intervention to 45% of eligible patients yields a projected active waitlist reduction of 41.4% over 3 years. Average bridge-patient wait time is safely extended to human graft availability, preventing chronic dialysis-related mortality.
File downloaded