D3 Educational Science Tool

Polygenic Embryo Selection Simulator

Explore statistical limits, sibling inheritance variance, and pleiotropic risk trade-offs when screening IVF embryo batches with Polygenic Risk Scores (PRS).

Sibling Trait Distribution & Trade-off Interactive Scatter
Expected Gain vs. Batch Size (N) Statistical Ceiling
Inspected Embryo Details Embryo #4 Selected

Click any embryo dot in the scatter plot above to compare individual polygenic predictions against correlated pleiotropic side-effects.

Embryo ID
#4
Target Trait Score
-1.80 SD
Complex Trait Index
112
Autoimmune Risk Delta
+1.50 SD

Polygenic Selection Summary

Computed live from current sibling batch genetics and selection parameters.

Diminishing Return Notice: Selection from 10 embryos yields ~1.24 SD shift, but sibling variance remains high due to random meiotic recombination.
Polygenic Gain (SD)
1.24
Pleiotropic Risk Shift
+0.40
Selected Embryo ID
4
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