Embryo Screening & Reproductive Tech Economics Simulator

Presets & Paradigms

Quantitative Parameters

Viable Blastocyst Yield (N): 8

Standard maternal age IVF yield yields 4–10 viable embryos for biopsy.

Target Trait:

Trait Heritability Bound (h²): 0.50

Limits phenotypic shift ($S_{actual} = i \cdot \sigma \cdot h^2$).

IVF Venture Unit Economics

Base IVF Cycle Cost ($): $18,000

PGT-P Screening Add-on ($): $7,500

The Finite Cohort Dilemma: With N=8 embryos, expected max selection intensity i is ~1.42 standard deviations. Over 50% of sibling variance is locked in Mendelian segregation noise.

Expected Trait Shift (Δσ)

+0.71 σ

Phenotypic Advantage

+3.5 pts

Correlated Risk Shift

+0.13 σ

Cost Per Realized SD Shift

$35,915

Biopsied Blastocyst Cohort (8 Generated) - Click to inspect individual embryo Green = Highest Selected Rank

Polygenic Score (PRS) Distribution & Selected Embryo Gaussian Population vs Cohort

Pleiotropic Trade-Off Scatter (Target vs Off-Target Risk) Genetic Correlation: r = +0.18

Silicon Valley Venture Model: IVF Market Penetration vs Biological Return Plateau TAM & Marginal Cost Efficiency Curve