GlyNAC & Glutathione Cellular Redox Simulator

Baylor College Research Model
Clinical Presets
Substrate & Stress Kinetics
Biological Age 72 yrs
N-Acetylcysteine (NAC) 100 mg/kg
Glycine Supplement 100 mg/kg
ROS Production Rate 8.5 arbitrary units
Mechanism Note: Glutathione (GSH) synthesis requires two rate-limiting enzymatic steps: 1) GCL combines Cysteine (from NAC) + Glutamate. 2) GS enzyme adds Glycine. Deficiency in either precursor severely limits intracellular GSH synthesis.
Cytosolic GSH Concentration -- μM Target: > 3.0 μM
Mitochondrial Membrane Potential -- mV Healthy: -160 to -180 mV
Lipid Peroxidation Damage Rate -- %/hr Lower is optimal
Cellular Redox Balance -- GSH:GSSG Ratio (Higher is healthier)
Live Intracellular Pathway & Organelle State
CYTOSOL Precursor Pool Cysteine (NAC): 100 Glycine: 100 GSH Synthesis Enzymes: GCL + GS GSH Pool: 1.2 μM Rate Limit: Balanced Mitochondrion ROS Scavenging: Optimal MMP (ΔΨm): -165 mV Lipid Damage: Low
GlyNAC & Glutathione Cellular Redox Summary
Loading cellular simulation model...
Enjoy this tool? Build your own with Super