Gut Microbiome Diversity & Probiotic Response Simulator

Gut Lumen & Mucosal Barrier Simulation Balanced Ecosystem

Substrate Fermentation: Active

Epithelial Barrier: Intact (92%)

Bacteroides

Faecalibacterium (Butyrate)

Bifidobacterium

Akkermansia (Mucus)

Opportunistic Pathobionts

Shannon Diversity (H')

2.84

High Species Richness

Total SCFA Production

74.2 mmol/L

60:20:20 (Ace:Pro:But)

Mucosa Thickness

145 μm

Protective Layer

Acetate (Energy & Substrate) 42.5 mmol/L

Propionate (Satiety & Metabolic Control) 15.8 mmol/L

Butyrate (Colonocyte Fuel & Anti-inflammatory) 15.9 mmol/L

Prebiotic Substrates & Probiotics

1. Dietary Prebiotic Fibers (g/day)

Inulin / Oligofructose (Bifidogenic) 15 g

Resistant Starch (Butyrate Stimulant) 20 g

Pectin & Soluble Fibers (Propionate) 10 g

Insoluble Cellulose (Bulking Transit) 5 g

2. Probiotic Strain Inoculation

B. infantis

Breaks down complex HMOs & inulin

F. prausnitzii

Key anti-inflammatory butyrate producer

A. muciniphila

Strengthens gut lining & mucin layer

L. rhamnosus

Produces lactate, lowers lumen pH

Diversity Index: Optimum diversity supported by varied fiber intake.
Barrier Health: Strong tight junction integrity. Low endotoxin leak potential.
Targeted Advice: Maintain resistant starch levels to sustain Faecalibacterium populations.