CRISPR Base Editor Screen & Barrier Knockout Explorer

19,144-Gene Screen · DNA Repair Pathway Knockout Simulation · Nature Comms / UW-Madison

19,144 Genes Screened
Genome-Wide Screen Volcano Plot Top 6 Barrier Roadblocks
Select obstacle genes below to perturb repair barriers (single or dual knockout):
Perturbation Response & Chromatogram UNG + MSH2 KO Active
Baseline Efficiency
11.4%
Perturbed Efficiency
71.8%
Efficiency Boost
6.30x
Product Purity
94.2%
Unmodified Target
26.1%
Unwanted Indels
2.1%
Protospacer:
Post-Edit:
Enjoy this tool? Build your own with Super