SAMe / SAH Ratio
4.20
Optimal Methylation Capacity
DNMT Activity Index
0.85
Enzyme Kinetics Active
TNF-α Transcription
0.18
Pro-inflammatory (Suppressed)
SOD2 Transcription
0.85
Antioxidant Defense (Elevated)
One-Carbon Substrate Cycle
Particle Flux
CpG Island Promoter & Polymerase View
DNA / Chromatin Structure
Cellular Transcriptomic & Phenotypic Outcome
Validated Calculation
| Target Gene | Function / Pathway | Promoter Methylation | Transcription Rate | State |
|---|---|---|---|---|
| TNF-α (Tumor Necrosis Factor) | Pro-inflammatory cytokine signaling | 82.0% | 0.18 mRNA/s | Suppressed |
| SOD2 (Superoxide Dismutase) | Mitochondrial antioxidant defense | 25.0% | 0.85 mRNA/s | Active |
Cellular Phenotype Summary: Optimal Methylation Capacity: Suppressed pro-inflammatory TNF-alpha transcription; elevated anti-oxidant SOD2 expression.
SAMe (Methyl Donor)
Methionine / 5-MTHF
Methyl Group (mC)
mRNA Wave / Polymerase