1. Parameter Configuration
350 mg
50 mg
350 mg (RDA)
600 mg
Stoichiometric Conversion
Total Salt Mass Required
2,482 mg
Elemental Mg %
14.1%
To achieve 350 mg of elemental magnesium using Mg Glycinate, a total compound pill mass of 2,482 mg is required due to the glycine carrier weight.
24-Hour Systemic Plasma Concentration Dynamics
Simulated plasma levels over 24 hours post-ingestion (mg/L increase above baseline)
BBB Penetration Index
8.8 / 10
High central nervous system uptake. Active transporter cross-rate optimized for synaptic tissue enrichment.
GI Osmotic Distress Index
12 / 100 (Low Risk)
Cheated organic structure prevents intestinal water draw, minimizing laxative or osmotic distress risk.
RCT Clinical Trial Evidence Mapping
Grade A Evidence
Primary Endpoint
Sleep Latency Reduction
-18.4 min average
Observed Bioavailability
High (Organic Chelate)
~24% absorption
Recommended Dose Range
200 - 400 mg / day
Evening administrationClinical trials demonstrate that organic amino-acid chelated magnesium (e.g., Glycinate) significantly reduces GABA-ergic inhibition thresholds, accelerating sleep onset latency without inducing osmotic intestinal distress.
Ref: Abbasi et al. (2012) J Res Med Sci; Nielsen et al. (2010) Magnes Res.