Clinical Schedule Mode
Cohort Presets
Simulation Parameters
Birth Cohort Size
10,000
Per-Visit Attrition / Dropout Rate
18.0%
Real-world pediatric drop-off per separate scheduled appointment
Split Shot Spacing Interval
3 months
Measles Reproduction (R₀)
15.0
Herd immunity threshold = 1 - 1/R₀ (93.3%)
Index Outbreak Seed Cases
5
Immunological Fact: Splitting MMR into 6 individual clinic visits compounds appointment non-completion, leaving toddlers vulnerable to measles during critical brain development months with zero biological benefit.
Measles Coverage (Dose 1)
94.0%
Threshold: 93.3% Required
Rubella Final Coverage
94.0%
After cumulative dropout
Vulnerability Window
36,000
Total Unprotected Person-Months
Measles Epidemic Risk
Contained
~0 Excess Cases
Pediatric Schedule & Cohort Retention
Standard 2-Dose Combined
● Measles (M)
● Mumps (Mu)
● Rubella (R)
--- Herd Threshold (93.3%)
Epidemic Transmission Wave (SEIR Model)
Herd Immunity Maintained
— Active Infectious
— Cumulative Cases
— Immune/Recovered
Antigenic Immune Burden: Science vs Myth
Combined MMR Total Antigens: ~25 proteins
< 0.002% capacity
Infants naturally process 2,000 - 6,000+ environmental antigens daily from breastmilk, dust, and gut microbiota. Combining MMR places zero excess strain on the immune system.
Window of Vulnerability: Under split regimens, delaying Mumps & Rubella inoculations by 3–6 months creates a dangerous window where infants are susceptible to severe viral complications without any immune benefit.
Antigen Protection Audit
| Antigen Dose | Age Target | Retention | Effective Coverage | Status |
|---|